Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Hampton (217) | 14 | Jackson State (136) | 28 | Final | W | 14 |
| 2 | 2025-09-06 | Jackson State (136) | 20 | Southern Miss (157) | 38 | Final | L | -18 |
| 3 | 2025-09-13 | Tuskegee | 0 | Jackson State (136) | 30 | Final | W | 30 |
| 4 | 2025-09-27 | Jackson State (174) | 38 | Southern (247) | 13 | Final | W | 25 |
| 5 | 2025-10-04 | Jackson State (157) | 57 | Alabama A&M (223) | 24 | Final | W | 33 |
| 6 | 2025-10-11 | Alabama State (170) | 34 | Jackson State (152) | 38 | Final | W | 4 |
| 7 | 2025-10-25 | Jackson State (170) | 24 | Grambling (199) | 26 | Final | L | -2 |
| 8 | 2025-11-01 | Jackson State (168) | 41 | Florida A&M (241) | 16 | Final | W | 25 |
| 9 | 2025-11-08 | Jackson State (166) | 42 | Mississippi Valley State (264) | 3 | Final | W | 39 |
| 10 | 2025-11-15 | Bethune-Cookman (220) | 13 | Jackson State (165) | 28 | Final | W | 15 |
| 11 | 2025-11-22 | Alcorn State (228) | 21 | Jackson State (164) | 27 | Final | W | 6 |
| 12 | 2025-12-06 | Prairie View A&M | 23 | Jackson State | 21 | Final | L | -2 |