College football is known for its great rivalries and strong matchups, but the first few weeks of any given season can often be overlooked outside of marquee matchups. But occasionally, history is still being made.
The biggest blowout in college football history is the famed 222-0 Georgia Tech win over Cumberland. Coached by John Heisman (yep, that Heisman), Georgia Tech hung 63 points in each quarter of the first half. The second half was shortened to 12 minute quarters, but Tech still managed to score on every possession. But Georgia Tech wasn't the only one putting big numbers on the scoreboards in the early days of college football: 54 schools on the list have won a game by 100 points or more in their history.
Note: I used FBS games only for teams that transitioned into or out of (and then back into). The modern era is from 1966 onwards (50 years prior to when this list was initially created). For errors, please make a comment below.
| Team | Point Differential | Opponent | Date | Score |
|---|---|---|---|---|
| Air Force | 72 | Nicholls State | 2009-09-05 | 72 - 0 |
| Akron | 62 | Western Reserve | 1893-11-01 | 66 - 4 |
| Alabama | 110 | Marion Military Institute | 1922-09-30 | 110 - 0 |
| Appalachian State | 66 | Campbell | 2014-09-06 | 66 - 0 |
| Arizona | 167 | Camp Harry Jones | 1920-10-16 | 167 - 0 |
| Arizona State | 99 | Casa Blanca Indians | 1932-10-01 | 99 - 0 |
| Arkansas | 100 | Missouri State | 1911-09-30 | 100 - 0 |
| Arkansas State | 101 | Central Arkansas | 1917-11-02 | 101 - 0 |
| Army | 90 | Bowdoin | 1920-11-13 | 90 - 0 |
| Auburn | 94 | Georgia Tech | 1894-11-17 | 94 - 0 |
| Ball State | 58 | Butler | 1967-10-21 | 65 - 7 |
| Baylor | 103 | Hardin-Simmons | 1917-10-27 | 103 - 0 |
| Boise State | 66 | Hawaii | 2004-10-29 | 69 - 3 |
| Boston College | 78 | Saint Anselm | 1941-09-20 | 78 - 0 |
| Bowling Green | 151 | Findlay | 1921-10-15 | 151 - 0 |
| Buffalo | 81 | Hobart | 1918-11-16 | 81 - 0 |
| BYU | 76 | UTEP | 1980-11-01 | 83 - 7 |
| California | 127 | Saint Mary's (CA) | 1920-10-09 | 127 - 0 |
| Central Florida | 63 | Liberty | 2001-10-13 | 63 - 0 |
| Central Michigan | 80 | Ferris State | 1920-10-09 | 80 - 0 |
| Charlotte | 35 | Massachusetts | 2019-09-14 | 52 - 17 |
| Cincinnati | 124 | Transylvania | 1912-10-05 | 124 - 0 |
| Clemson | 122 | Guilford | 1901-10-05 | 122 - 0 |
| Colorado | 109 | Regis | 1905-10-07 | 109 - 0 |
| Connecticut | 125 | Newport NTS | 1949-10-22 | 125 - 0 |
| Duke | 96 | Furman | 1891-11-14 | 96 - 0 |
| East Carolina | 74 | Newport News Apprentice School | 1959-11-14 | 74 - 0 |
| Eastern Michigan | 76 | Toledo AA | 1894-11-03 | 76 - 0 |
| Florida | 144 | Florida Southern | 1913-10-06 | 144 - 0 |
| Florida Atlantic | 48 | Siena | 2003-11-15 | 51 - 3 |
| Florida International | 46 | FAU | 2005-11-26 | 52 - 6 |
| Florida State | 74 | Whiting Field NAS | 1949-10-01 | 74 - 0 |
| Fresno State | 80 | Fort Ord | 1942-10-24 | 80 - 0 |
| Georgia | 108 | Alabam Presbyterian | 1913-10-04 | 108 - 0 |
| Georgia Southern | 74 | Savannah State | 2014-09-06 | 83 - 9 |
| Georgia State | 34 | Savannah State | 2010-10-09 | 55 - 21 |
| Georgia Tech | 222 | Cumberland | 1916-10-07 | 222 - 0 |
| Hawaii | 101 | Field Artillery | 1926-10-02 | 101 - 0 |
| Houston | 94 | Tulsa | 1968-11-28 | 100 - 6 |
| Idaho | 83 | College of Idaho | 1923-10-06 | 83 - 0 |
| Illinois | 84 | Illinois Wesleyan | 1912-10-05 | 87 - 3 |
| Indiana | 76 | Franklin | 1901-10-19 | 76 - 0 |
| Iowa | 95 | Northern Iowa | 1914-10-03 | 95 - 0 |
| Iowa State | 87 | Simpson | 1904-10-02 | 87 - 0 |
| Kansas | 83 | Washington (MO) | 1923-11-10 | 83 - 0 |
| Kansas State | 76 | Ball State | 2000-09-16 | 76 - 0 |
| Kent State | 65 | Western Reserve | 1954-10-01 | 65 - 0 |
| Kentucky | 87 | Wilmington | 1914-09-26 | 87 - 0 |
| Louisiana | 105 | Delcambre Academy | 1903-11-04 | 105 - 0 |
| Louisiana Tech | 100 | Clarke Memorial College | 1905-04-05 | 100 - 0 |
| Louisiana-Monroe | 66 | Ouachita Baptist | 1905-05-04 | 66 - 0 |
| Louisville | 100 | Washington College Academy (TN) | 1913-10-18 | 100 - 0 |
| LSU | 93 | Louisiana-Lafayette | 1936-11-21 | 93 - 0 |
| Marshall | 101 | Kentucky Wesleyan | 1916-10-21 | 101 - 0 |
| Maryland | 80 | Washington (MD) | 1927-09-24 | 80 - 0 |
| Massachusetts | 77 | Wagner | 1931-11-14 | 77 - 0 |
| Memphis | 115 | Somerville HS | 1916-10-14 | 115 - 0 |
| Miami | 77 | Savannah State | 2018-09-08 | 77 - 0 |
| Miami (OH) | 91 | Earlham | 1917-10-20 | 91 - 0 |
| Michigan | 130 | West Virginia | 1904-10-22 | 130 - 0 |
| Michigan State | 109 | Olivet | 1920-10-30 | 109 - 0 |
| Middle Tennessee | 72 | North Alabama | 1905-04-10 | 72 - 0 |
| Minnesota | 146 | Grinnell | 1904-10-22 | 146 - 0 |
| Mississippi State | 82 | Samford | 1910-11-18 | 82 - 0 |
| Missouri | 90 | Missouri Engineer Institute | 1890-12-01 | 90 - 0 |
| Navy | 127 | Ursinus | 1918-11-16 | 127 - 0 |
| Nebraska | 119 | Haskell Indian Nations | 1910-11-24 | 119 - 0 |
| Nevada | 132 | Pacific | 1919-10-15 | 132 - 0 |
| New Mexico | 108 | Northern Arizona | 1916-11-11 | 108 - 0 |
| New Mexico State | 116 | Fort Bliss | 1905-03-26 | 116 - 0 |
| North Carolina | 66 | Idaho | 2012-09-29 | 66 - 0 |
| North Carolina State | 100 | Hampton Roads 5th Naval District | 1919-10-11 | 100 - 0 |
| North Texas | 98 | Decatur Baptist | 1929-10-04 | 98 - 0 |
| Northern Illinois | 107 | Wheaton | 1912-10-18 | 114 - 7 |
| Northwestern | 97 | Wisconsin-Oshkosh | 1904-11-05 | 97 - 0 |
| Notre Dame | 142 | American Medical | 1905-10-28 | 142 - 0 |
| Ohio | 86 | Wittenberg | 1916-11-04 | 89 - 3 |
| Ohio State | 128 | Oberlin | 1916-10-14 | 128 - 0 |
| Oklahoma | 179 | Kingfisher | 1917-09-29 | 179 - 0 |
| Oklahoma State | 134 | Phillips | 1914-10-09 | 134 - 0 |
| Old Dominion | 63 | Virginia Military | 2018-11-17 | 77 - 14 |
| Ole Miss | 114 | Union | 1904-10-29 | 114 - 0 |
| Oregon | 115 | Puget Sound | 1910-10-22 | 115 - 0 |
| Oregon State | 76 | Williamette | 1931-09-19 | 76 - 0 |
| Penn State | 109 | Lebanon Valley | 1920-10-23 | 109 - 0 |
| Pitt | 96 | Dickinson | 1914-10-31 | 96 - 0 |
| Purdue | 96 | Butler | 1893-10-21 | 96 - 0 |
| Rice | 143 | SMU | 1916-11-17 | 146 - 3 |
| Rutgers | 96 | Rensselaer Tech | 1915-10-09 | 96 - 0 |
| San Diego State | 72 | UCSB | 1953-11-21 | 72 - 0 |
| San Jose State | 103 | University of Mexico | 1949-09-10 | 103 - 0 |
| SMU | 70 | Daniel Baker | 1920-09-25 | 70 - 0 |
| South Alabama | 52 | Southern Miss | 2023-10-17 | 55 - 3 |
| South Carolina | 89 | Welch Neck Academy | 1903-10-06 | 89 - 0 |
| South Florida | 59 | Charleston Southern | 2009-09-19 | 59 - 0 |
| Southern Miss | 113 | Raleigh Smith County HS | 1921-10-15 | 113 - 0 |
| Stanford | 82 | Mare Island Marines, UCLA | 1923-09-29 | 82 - 0 |
| Syracuse | 144 | Manhattan | 1904-11-05 | 144 - 0 |
| TCU | 69 | New Mexico | 2011-10-22 | 69 - 0 |
| Temple | 110 | Blue Ridge | 1927-10-01 | 110 - 0 |
| Tennessee | 104 | American University (TN) | 1905-10-07 | 104 - 0 |
| Texas | 92 | Daniel Baker | 1915-10-09 | 92 - 0 |
| Texas A&M | 110 | Daniel Baker | 1920-10-02 | 110 - 0 |
| Texas State | 79 | Meridian College | 1905-04-03 | 79 - 0 |
| Texas Tech | 120 | Wayland Baptist | 1925-11-05 | 120 - 0 |
| Toledo | 88 | Davis & Elkins | 1951-09-15 | 88 - 0 |
| Troy | 76 | Concord | 1968-11-16 | 76 - 0 |
| Tulane | 95 | Louisiana-Lafayette | 1912-10-12 | 95 - 0 |
| Tulsa | 152 | Oklahoma Baptist | 1919-09-27 | 152 - 0 |
| UAB | 59 | Alabama A&M | 2022-09-01 | 59 - 0 |
| UCLA | 72 | Stanford | 1954-10-16 | 72 - 0 |
| UNLV | 72 | Idaho State | 2015-09-26 | 80 - 8 |
| USC | 80 | Pomona-Pitzer | 1925-10-03 | 80 - 0 |
| Utah | 129 | Fort Douglas | 1905-10-28 | 129 - 0 |
| Utah State | 136 | Idaho State | 1919-10-11 | 136 - 0 |
| UTEP | 85 | New Mexico State | 1948-11-25 | 92 - 7 |
| UTSA | 54 | Lamar | 2021-09-11 | 54 - 0 |
| Vanderbilt | 105 | Bethel | 1912-09-28 | 105 - 0 |
| Virginia | 136 | Randolph-Macon | 1890-11-24 | 136 - 0 |
| Virginia Military | 63 | Old Dominion | 2018-11-17 | 77 - 14 |
| Virginia Tech | 99 | Emory & Henry | 1919-11-22 | 99 - 0 |
| Wake Forest | 80 | Atlantic Coast Line YMCA | 1915-09-25 | 80 - 0 |
| Washington | 120 | Whitman | 1919-10-25 | 120 - 0 |
| Washington State | 86 | Blair Business College | 1907-10-12 | 86 - 0 |
| West Virginia | 89 | Geneva | 1951-10-20 | 89 - 0 |
| Western Kentucky | 73 | Florida International | 2022-09-24 | 73 - 0 |
| Western Michigan | 103 | Hillsdale | 1918-11-16 | 103 - 0 |
| Wisconsin | 106 | Wisconsin-Whitewater | 1890-11-01 | 106 - 0 |
| Wyoming | 103 | Northern Colorado | 1949-11-05 | 103 - 0 |