Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2026-08-27 | Southern Illinois (157) | 31 | West Florida | 34 | Final | L | -3 |
| 2 | 2026-09-03 | Southern Illinois (157) | 22 | Samford (255) | 18 | Final | W | 4 |
| 3 | 2026-09-12 | Southeast Missouri State (218) | 20 | Southern Illinois (157) | 34 | Final | W | 14 |
| 4 | 2026-09-19 | Southern Illinois (157) | Illinois (24) | Scheduled - 1:00 PM | - | - | ||
| 5 | 2026-09-26 | Southern Illinois | Murray State | Scheduled - 6:00 PM | - | - | ||
| 6 | 2026-10-03 | Youngstown State | Southern Illinois | Scheduled - 4:00 PM | - | - | ||
| 7 | 2026-10-10 | Southern Illinois | South Dakota | Scheduled - 1:00 PM | - | - | ||
| 8 | 2026-10-16 | Illinois State | Southern Illinois | Scheduled - TBD | - | - | ||
| 9 | 2026-10-24 | Northern Iowa | Southern Illinois | Scheduled - 1:00 PM | - | - | ||
| 10 | 2026-11-07 | Southern Illinois | Indiana State | Scheduled - 6:00 PM | - | - | ||
| 11 | 2026-11-14 | South Dakota State | Southern Illinois | Scheduled - 1:00 PM | - | - | ||
| 12 | 2026-11-21 | Southern Illinois | North Dakota | Scheduled - 1:00 PM | - | - |