Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2026-09-05 | Southeast Missouri State (218) | 10 | Iowa State (34) | 38 | Final | W | 28 |
| 2 | 2026-09-12 | Iowa State (34) | 13 | Iowa (21) | 16 | Final | L | -3 |
| 3 | 2026-09-19 | Bowling Green (157) | 7 | Iowa State (80) | 55 | Final | W | 48 |
| 4 | 2026-09-26 | Utah (13) | 31 | Iowa State (80) | 17 | Final | L | -14 |
| 5 | 2026-10-03 | West Virginia (68) | 42 | Iowa State (60) | 45 | Final | W | 3 |
| 6 | 2026-10-09 | Iowa State (63) | 10 | BYU (9) | 24 | Final | L | -14 |
| 7 | 2026-10-24 | Iowa State (77) | 3 | Arizona (18) | 39 | Final | L | -36 |
| 8 | 2026-10-31 | Oklahoma State (23) | Iowa State (77) | Scheduled - 6:00 PM | - | - | ||
| 9 | 2026-11-06 | Iowa State | Baylor | Scheduled - TBD | - | - | ||
| 10 | 2026-11-13 | Cincinnati | Iowa State | Scheduled - TBD | - | - | ||
| 11 | 2026-11-20 | Iowa State | Central Florida | Scheduled - 6:00 PM | - | - | ||
| 12 | 2026-11-27 | Kansas State | Iowa State | Scheduled - TBD | - | - |