Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Sul Ross State | 0 | UTRGV | 66 | Final | W | 66 |
| 2 | 2025-09-06 | UTRGV | 27 | Prairie View A&M (236) | 21 | Final | W | 6 |
| 3 | 2025-09-13 | Langston | 0 | UTRGV | 80 | Final | W | 80 |
| 4 | 2025-09-20 | Texas Wesleyan | 13 | UTRGV (148) | 61 | Final | W | 48 |
| 5 | 2025-09-27 | UTRGV (159) | 31 | Southeastern Louisiana (150) | 45 | Final | L | -14 |
| 6 | 2025-10-04 | Houston Christian (237) | 7 | UTRGV (154) | 27 | Final | W | 20 |
| 7 | 2025-10-18 | UTRGV (163) | 21 | Lamar (140) | 23 | Final | L | -2 |
| 8 | 2025-10-25 | Incarnate Word (220) | 28 | UTRGV (157) | 56 | Final | W | 28 |
| 9 | 2025-11-01 | UTRGV (169) | 17 | Stephen F. Austin (142) | 41 | Final | L | -24 |
| 10 | 2025-11-08 | Nicholls State (205) | 21 | UTRGV (163) | 28 | Final | W | 7 |
| 11 | 2025-11-15 | UTRGV (163) | 28 | McNeese (218) | 13 | Final | W | 15 |
| 12 | 2025-11-22 | East Texas A&M (232) | 14 | UTRGV (172) | 33 | Final | W | 19 |