Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Prairie View A&M (236) | 22 | Texas Southern (230) | 21 | Final | L | -1 |
| 2 | 2025-09-06 | Texas Southern (230) | 3 | California (82) | 35 | Final | L | -32 |
| 3 | 2025-09-13 | Lamar (181) | 31 | Texas Southern (230) | 7 | Final | L | -24 |
| 4 | 2025-09-27 | Texas Southern (226) | 23 | Mississippi Valley State (262) | 20 | Final | W | 3 |
| 5 | 2025-10-04 | Arkansas-Pine Bluff (261) | 7 | Texas Southern (206) | 51 | Final | W | 44 |
| 6 | 2025-10-11 | Texas Southern (198) | 21 | Grambling (231) | 20 | Final | W | 1 |
| 7 | 2025-10-18 | Virginia Lynchburg | 10 | Texas Southern (186) | 61 | Final | W | 51 |
| 8 | 2025-11-01 | Alcorn State (237) | 33 | Texas Southern (217) | 14 | Final | L | -19 |
| 9 | 2025-11-08 | Texas Southern (220) | 24 | Alabama State (155) | 42 | Final | L | -18 |
| 10 | 2025-11-15 | Texas Southern (215) | 35 | Southern (259) | 30 | Final | W | 5 |
| 11 | 2025-11-22 | Alabama A&M (244) | 7 | Texas Southern (214) | 24 | Final | W | 17 |