Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | North Carolina A&T (257) | 21 | Tennessee State (171) | 24 | Final | W | 3 |
| 2 | 2025-09-06 | North Dakota State (69) | 59 | Tennessee State (171) | 3 | Final | L | -56 |
| 3 | 2025-09-13 | Alabama A&M (225) | 23 | Tennessee State (171) | 21 | Final | L | -2 |
| 4 | 2025-09-27 | Tennessee Tech (142) | 35 | Tennessee State (235) | 8 | Final | L | -27 |
| 5 | 2025-10-04 | Tennessee State (240) | 7 | Eastern Illinois (199) | 31 | Final | L | -24 |
| 6 | 2025-10-11 | Tennessee State (245) | 12 | Southeast Missouri State (222) | 28 | Final | L | -16 |
| 7 | 2025-10-18 | Howard (257) | 7 | Tennessee State (241) | 24 | Final | W | 17 |
| 8 | 2025-10-25 | Western Illinois (243) | 17 | Tennessee State (244) | 16 | Final | L | -1 |
| 9 | 2025-11-01 | Lindenwood (181) | 35 | Tennessee State (248) | 13 | Final | L | -22 |
| 10 | 2025-11-08 | Tennessee State (251) | 7 | Tennessee-Martin (175) | 26 | Final | L | -19 |
| 11 | 2025-11-15 | Gardner-Webb (168) | 30 | Tennessee State (250) | 14 | Final | L | -16 |
| 12 | 2025-11-22 | Tennessee State (252) | 6 | Charleston Southern (200) | 7 | Final | L | -1 |