Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-28 | Boise State (11) | 7 | South Florida (85) | 34 | Final | W | 27 |
| 2 | 2025-09-06 | South Florida (85) | 18 | Florida (25) | 16 | Final | W | 2 |
| 3 | 2025-09-13 | South Florida (85) | 12 | Miami (15) | 49 | Final | L | -37 |
| 4 | 2025-09-20 | South Carolina State (177) | 14 | South Florida (43) | 63 | Final | W | 49 |
| 5 | 2025-10-03 | Charlotte (138) | 26 | South Florida (33) | 54 | Final | W | 28 |
| 6 | 2025-10-10 | South Florida (17) | 63 | North Texas (32) | 36 | Final | W | 27 |
| 7 | 2025-10-18 | Florida Atlantic (105) | 13 | South Florida (14) | 48 | Final | W | 35 |
| 8 | 2025-10-25 | South Florida (21) | 31 | Memphis (33) | 34 | Final | L | -3 |
| 9 | 2025-11-06 | UTSA (82) | 23 | South Florida (21) | 55 | Final | W | 32 |
| 10 | 2025-11-15 | South Florida (26) | 38 | Navy (36) | 41 | Final | L | -3 |
| 11 | 2025-11-22 | South Florida (22) | 48 | UAB (120) | 18 | Final | W | 30 |
| 12 | 2025-11-29 | Rice (102) | 3 | South Florida (20) | 52 | Final | W | 49 |
| 13 | 2025-12-17 | Old Dominion (41) | 24 | South Florida (20) | 10 | Final | L | -14 |