Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Nevada (121) | 11 | Penn State (5) | 46 | Final | W | 35 |
| 2 | 2025-09-06 | Florida International (129) | 0 | Penn State (5) | 34 | Final | W | 34 |
| 3 | 2025-09-13 | Villanova (148) | 6 | Penn State (5) | 52 | Final | W | 46 |
| 4 | 2025-09-27 | Oregon (8) | 30 | Penn State (42) | 24 | Final/2OT | L | -6 |
| 5 | 2025-10-04 | Penn State (75) | 37 | UCLA (104) | 42 | Final | L | -5 |
| 6 | 2025-10-11 | Northwestern (48) | 22 | Penn State (80) | 21 | Final | L | -1 |
| 7 | 2025-10-18 | Penn State (75) | 24 | Iowa (37) | 25 | Final | L | -1 |
| 8 | 2025-11-01 | Penn State (80) | 14 | Ohio State (2) | 38 | Final | L | -24 |
| 9 | 2025-11-08 | Indiana (1) | 27 | Penn State (72) | 24 | Final | L | -3 |
| 10 | 2025-11-15 | Penn State (62) | 28 | Michigan State (101) | 10 | Final | W | 18 |
| 11 | 2025-11-22 | Nebraska (41) | 10 | Penn State (46) | 37 | Final | W | 27 |
| 12 | 2025-11-29 | Penn State (40) | 40 | Rutgers (69) | 36 | Final | W | 4 |
| 13 | 2025-12-27 | Penn State (40) | 22 | Clemson (53) | 10 | Final | W | 12 |