Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-08-30 | Louisiana Christian | 9 | McNeese (185) | 54 | Final | W | 45 |
| 2 | 2025-09-06 | McNeese (185) | 10 | Louisiana (54) | 34 | Final | L | -24 |
| 3 | 2025-09-13 | Weber State (214) | 42 | McNeese (185) | 41 | Final | L | -1 |
| 4 | 2025-09-20 | McNeese (215) | 7 | Utah State (55) | 48 | Final | L | -41 |
| 5 | 2025-09-27 | McNeese (231) | 17 | Stephen F. Austin (162) | 34 | Final | L | -17 |
| 6 | 2025-10-04 | Southeastern Louisiana (148) | 38 | McNeese (234) | 0 | Final | L | -38 |
| 7 | 2025-10-18 | Houston Christian (242) | 0 | McNeese (228) | 27 | Final | W | 27 |
| 8 | 2025-10-25 | McNeese (235) | 7 | Nicholls State (218) | 31 | Final | L | -24 |
| 9 | 2025-11-01 | Northwestern State (258) | 3 | McNeese (227) | 50 | Final | W | 47 |
| 10 | 2025-11-08 | McNeese (218) | 35 | East Texas A&M (233) | 20 | Final | W | 15 |
| 11 | 2025-11-15 | UTRGV (163) | 28 | McNeese (218) | 13 | Final | L | -15 |
| 12 | 2025-11-22 | McNeese (206) | 21 | Lamar (166) | 19 | Final | W | 2 |