Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-03 | Fairfield (312) | 68 | 76 | Penn State (68) | Final | W | 8 |
| 2 | 2025-11-08 | Penn State (68) | 87 | 43 | New Haven | Final | W | 44 |
| 3 | 2025-11-11 | Navy (285) | 71 | 80 | Penn State (68) | Final | W | 9 |
| 4 | 2025-11-15 | Penn State (68) | 83 | 69 | La Salle (185) | Final | W | 14 |
| 5 | 2025-11-19 | Harvard (249) | 80 | 84 | Penn State (68) | Final | W | 4 |
| 6 | 2025-11-22 | Providence (122) | 77 | 65 | Penn State (68) | Final | L | -12 |
| 7 | 2025-11-25 | Boston University (277) | 87 | 96 | Penn State (68) | Final | W | 9 |
| 8 | 2025-11-29 | Sacred Heart (267) | 59 | 90 | Penn State (68) | Final | W | 31 |
| 9 | 2025-12-02 | Campbell (212) | 76 | 87 | Penn State (79) | Final | W | 11 |
| 10 | 2025-12-09 | Penn State (70) | 72 | 113 | Indiana (45) | Final | L | -41 |
| 11 | 2025-12-13 | Michigan State (7) | 76 | 72 | Penn State (70) | Final | L | -4 |
| 12 | 2025-12-21 | Pittsburgh (125) | 80 | 46 | Penn State (132) | Final | L | -34 |
| 13 | 2025-12-29 | North Carolina Central (339) | 67 | 90 | Penn State (135) | Final | W | 23 |
| 14 | 2026-01-03 | Illinois (14) | 73 | 65 | Penn State (135) | Final | L | -8 |
| 15 | 2026-01-06 | Michigan (1) | 74 | 72 | Penn State (122) | Final | L | -2 |
| 16 | 2026-01-10 | Penn State (122) | 85 | 93 | Purdue (7) | Final | L | -8 |
| 17 | 2026-01-14 | UCLA (55) | 71 | 60 | Penn State (106) | Final | L | -11 |
| 18 | 2026-01-18 | Penn State (125) | 73 | 96 | Maryland (138) | Final | L | -23 |
| 19 | 2026-01-22 | Wisconsin (36) | 98 | 71 | Penn State (125) | Final | L | -27 |
| 20 | 2026-01-26 | Penn State (137) | 78 | 84 | Ohio State (41) | Final | L | -6 |
| 21 | 2026-01-29 | Penn State (137) | 73 | 94 | Northwestern (89) | Final | L | -21 |
| 22 | 2026-02-01 | Minnesota (94) | 75 | 77 | Penn State (128) | Final | W | 2 |
| 23 | 2026-02-05 | Penn State (128) | 69 | 110 | Michigan (2) | Final | L | -41 |
| 24 | 2026-02-08 | USC (43) | 77 | 75 | Penn State (135) | Final | L | -2 |
| 25 | 2026-02-11 | Penn State (135) | 63 | 60 | Washington (63) | Final | W | 3 |
| 26 | 2026-02-14 | Penn State (135) | 72 | 83 | Oregon (101) | Final | L | -11 |
| 27 | 2026-02-18 | Rutgers (122) | 85 | 72 | Penn State (124) | Final | L | -13 |
| 28 | 2026-02-21 | Penn State (124) | 64 | 87 | Nebraska (8) | Final | L | -23 |
| 29 | 2026-02-28 | Iowa (34) | 69 | 71 | Penn State (132) | Final | W | 2 |
| 30 | 2026-03-04 | Ohio State (37) | 94 | 62 | Penn State (120) | Final | L | -32 |
| 31 | 2026-03-08 | Penn State (128) | 62 | 74 | Rutgers (115) | Final | L | -12 |
| 32 | 2026-03-10 | Penn State (128) | 66 | 76 | Northwestern (83) | Final | L | -10 |