Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-03 | Colgate (266) | 69 | 80 | Michigan State (7) | Final | W | 11 |
| 2 | 2025-11-08 | Arkansas (31) | 66 | 69 | Michigan State (7) | Final | W | 3 |
| 3 | 2025-11-13 | San Jose State (177) | 60 | 79 | Michigan State (7) | Final | W | 19 |
| 4 | 2025-11-18 | Michigan State (7) | 83 | 66 | Kentucky (9) | Final | W | 17 |
| 5 | 2025-11-21 | Detroit (328) | 56 | 84 | Michigan State (7) | Final | W | 28 |
| 6 | 2025-11-25 | Michigan State (7) | 89 | 56 | East Carolina (164) | Final | W | 33 |
| 7 | 2025-11-27 | Michigan State (7) | 74 | 58 | North Carolina (40) | Final | W | 16 |
| 8 | 2025-12-02 | Iowa (15) | 52 | 71 | Michigan State (6) | Final | W | 19 |
| 9 | 2025-12-06 | Duke (2) | 66 | 60 | Michigan State (6) | Final | L | -6 |
| 10 | 2025-12-13 | Michigan State (7) | 76 | 72 | Penn State (70) | Final | W | 4 |
| 11 | 2025-12-16 | Toledo (157) | 69 | 92 | Michigan State (9) | Final | W | 23 |
| 12 | 2025-12-20 | Oakland (136) | 70 | 79 | Michigan State (9) | Final | W | 9 |
| 13 | 2025-12-29 | Cornell (185) | 97 | 114 | Michigan State (10) | Final | W | 17 |
| 14 | 2026-01-02 | Michigan State (10) | 56 | 58 | Nebraska (8) | Final | L | -2 |
| 15 | 2026-01-05 | USC (27) | 51 | 80 | Michigan State (11) | Final | W | 29 |
| 16 | 2026-01-08 | Northwestern (103) | 66 | 76 | Michigan State (11) | Final | W | 10 |
| 17 | 2026-01-13 | Indiana (44) | 60 | 81 | Michigan State (11) | Final | W | 21 |
| 18 | 2026-01-17 | Michigan State (11) | 80 | 63 | Washington (71) | Final | W | 17 |
| 19 | 2026-01-20 | Michigan State (8) | 68 | 52 | Oregon (97) | Final | W | 16 |
| 20 | 2026-01-24 | Maryland (138) | 48 | 91 | Michigan State (8) | Final | W | 43 |
| 21 | 2026-01-27 | Michigan State (7) | 88 | 79 | Rutgers (135) | Final/OT | W | 9 |
| 22 | 2026-01-30 | Michigan (4) | 83 | 71 | Michigan State (7) | Final | L | -12 |
| 23 | 2026-02-04 | Michigan State (9) | 73 | 76 | Minnesota (94) | Final | L | -3 |
| 24 | 2026-02-07 | Illinois (7) | 82 | 85 | Michigan State (9) | Final/OT | W | 3 |
| 25 | 2026-02-13 | Michigan State (10) | 71 | 92 | Wisconsin (39) | Final | L | -21 |
| 26 | 2026-02-17 | UCLA (41) | 59 | 82 | Michigan State (12) | Final | W | 23 |
| 27 | 2026-02-22 | Ohio State (42) | 60 | 66 | Michigan State (10) | Final | W | 6 |
| 28 | 2026-02-26 | Michigan State (10) | 76 | 74 | Purdue (8) | Final | W | 2 |
| 29 | 2026-03-01 | Michigan State (8) | 77 | 64 | Indiana (47) | Final | W | 13 |
| 30 | 2026-03-05 | Rutgers (122) | 87 | 91 | Michigan State (8) | Final | W | 4 |
| 31 | 2026-03-08 | Michigan State (8) | 80 | 90 | Michigan (1) | Final | L | -10 |
| 32 | 2026-03-13 | UCLA (32) | 88 | 84 | Michigan State (8) | Final | L | -4 |
| 33 | 2026-03-19 | North Dakota State (106) | 67 | 92 | Michigan State (9) | Final | W | 25 |
| 34 | 2026-03-21 | Louisville (21) | 69 | 77 | Michigan State (9) | Final | W | 8 |
| 35 | 2026-03-27 | Michigan State (9) | 63 | 67 | Connecticut (8) | Final | L | -4 |