Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-03 | Cleveland State (148) | 88 | 91 | Loyola-Chicago (92) | Final | W | 3 |
| 2 | 2025-11-06 | Mercyhurst (321) | 73 | 65 | Loyola-Chicago (92) | Final | L | -8 |
| 3 | 2025-11-09 | North Texas (73) | 64 | 62 | Loyola-Chicago (92) | Final | L | -2 |
| 4 | 2025-11-13 | Loyola-Chicago (92) | 74 | 95 | Wichita State (134) | Final | L | -21 |
| 5 | 2025-11-16 | Colorado State (44) | 80 | 67 | Loyola-Chicago (92) | Final | L | -13 |
| 6 | 2025-11-21 | Northern Illinois (348) | 76 | 59 | Loyola-Chicago (92) | Final | L | -17 |
| 7 | 2025-11-25 | Northern Iowa (100) | 72 | 51 | Loyola-Chicago (92) | Final | L | -21 |
| 8 | 2025-11-26 | San Jose State (177) | 63 | 51 | Loyola-Chicago (92) | Final | L | -12 |
| 9 | 2025-12-02 | Central Michigan (299) | 72 | 83 | Loyola-Chicago (360) | Final | W | 11 |
| 10 | 2025-12-06 | Princeton (285) | 68 | 73 | Loyola-Chicago (360) | Final | W | 5 |
| 11 | 2025-12-14 | Chicago State (333) | 84 | 75 | Loyola-Chicago (341) | Final | L | -9 |
| 12 | 2025-12-17 | Loyola-Chicago (341) | 71 | 85 | San Francisco (138) | Final | L | -14 |
| 13 | 2025-12-20 | Loyola-Chicago (341) | 80 | 78 | Santa Clara (57) | Final | W | 2 |
| 14 | 2025-12-31 | Loyola-Chicago (318) | 61 | 57 | Rhode Island (101) | Final | W | 4 |
| 15 | 2026-01-03 | Dayton (91) | 70 | 68 | Loyola-Chicago (318) | Final | L | -2 |
| 16 | 2026-01-07 | Davidson (118) | 79 | 64 | Loyola-Chicago (283) | Final | L | -15 |
| 17 | 2026-01-10 | Loyola-Chicago (283) | 66 | 101 | George Washington (73) | Final | L | -35 |
| 18 | 2026-01-13 | George Mason (42) | 82 | 74 | Loyola-Chicago (296) | Final | L | -8 |
| 19 | 2026-01-16 | Loyola-Chicago (296) | 51 | 78 | Dayton (75) | Final | L | -27 |
| 20 | 2026-01-20 | Loyola-Chicago (305) | 70 | 84 | St. Bonaventure (154) | Final | L | -14 |
| 21 | 2026-01-24 | Duquesne (164) | 71 | 59 | Loyola-Chicago (305) | Final | L | -12 |
| 22 | 2026-01-27 | Saint Joseph's (160) | 85 | 64 | Loyola-Chicago (315) | Final | L | -21 |
| 23 | 2026-01-30 | Loyola-Chicago (315) | 75 | 89 | Virginia Commonwealth (54) | Final | L | -14 |
| 24 | 2026-02-03 | La Salle (267) | 61 | 71 | Loyola-Chicago (342) | Final | W | 10 |
| 25 | 2026-02-06 | Loyola-Chicago (342) | 64 | 84 | Davidson (118) | Final | L | -20 |
| 26 | 2026-02-13 | Saint Louis (16) | 86 | 59 | Loyola-Chicago (333) | Final | L | -27 |
| 27 | 2026-02-18 | Loyola-Chicago (330) | 59 | 62 | Fordham (219) | Final | L | -3 |
| 28 | 2026-02-21 | Loyola-Chicago (330) | 61 | 75 | Saint Joseph's (181) | Final | L | -14 |
| 29 | 2026-02-28 | Richmond (194) | 66 | 69 | Loyola-Chicago (333) | Final | W | 3 |
| 30 | 2026-03-04 | Loyola-Chicago (327) | 65 | 79 | Saint Louis (30) | Final | L | -14 |
| 31 | 2026-03-07 | George Washington | 62 | 68 | Loyola-Chicago (327) | Final | W | 6 |
| 32 | 2026-03-11 | Loyola-Chicago (326) | 75 | 67 | Richmond (226) | Final | W | 8 |
| 33 | 2026-03-12 | Loyola-Chicago (326) | 59 | 64 | Davidson (127) | Final/OT | L | -5 |