Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-03 | Fairleigh Dickinson (319) | 50 | 88 | Iowa State (19) | Final | W | 38 |
| 2 | 2025-11-06 | Grambling (336) | 62 | 102 | Iowa State (19) | Final | W | 40 |
| 3 | 2025-11-10 | Mississippi State (30) | 80 | 96 | Iowa State (19) | Final | W | 16 |
| 4 | 2025-11-17 | Stonehill (310) | 57 | 96 | Iowa State (19) | Final | W | 39 |
| 5 | 2025-11-24 | Iowa State (19) | 83 | 82 | St. John's (8) | Final | W | 1 |
| 6 | 2025-11-25 | Creighton (32) | 60 | 78 | Iowa State (19) | Final | W | 18 |
| 7 | 2025-11-26 | Syracuse (121) | 64 | 95 | Iowa State (19) | Final | W | 31 |
| 8 | 2025-12-03 | Alcorn State (338) | 68 | 132 | Iowa State (12) | Final | W | 64 |
| 9 | 2025-12-06 | Iowa State (12) | 81 | 58 | Purdue (3) | Final | W | 23 |
| 10 | 2025-12-11 | Iowa (23) | 62 | 66 | Iowa State (5) | Final | W | 4 |
| 11 | 2025-12-14 | Eastern Illinois (337) | 53 | 78 | Iowa State (4) | Final | W | 25 |
| 12 | 2025-12-21 | Long Beach State (293) | 60 | 91 | Iowa State (3) | Final | W | 31 |
| 13 | 2025-12-29 | Houston Christian (317) | 61 | 89 | Iowa State (3) | Final | W | 28 |
| 14 | 2026-01-02 | West Virginia (105) | 59 | 80 | Iowa State (3) | Final | W | 21 |
| 15 | 2026-01-07 | Iowa State (3) | 70 | 60 | Baylor (55) | Final | W | 10 |
| 16 | 2026-01-10 | Oklahoma State (40) | 71 | 83 | Iowa State (3) | Final | W | 12 |
| 17 | 2026-01-13 | Iowa State (2) | 63 | 84 | Kansas (30) | Final | L | -21 |
| 18 | 2026-01-17 | Iowa State (2) | 70 | 79 | Cincinnati (107) | Final | L | -9 |
| 19 | 2026-01-20 | Central Florida (21) | 57 | 87 | Iowa State (11) | Final | W | 30 |
| 20 | 2026-01-24 | Iowa State (11) | 84 | 71 | Oklahoma State (41) | Final | W | 13 |
| 21 | 2026-01-29 | Colorado (78) | 67 | 97 | Iowa State (9) | Final | W | 30 |
| 22 | 2026-02-01 | Iowa State (8) | 95 | 61 | Kansas State (77) | Final | W | 34 |
| 23 | 2026-02-07 | Baylor (63) | 69 | 72 | Iowa State (8) | Final | W | 3 |
| 24 | 2026-02-10 | Iowa State (5) | 55 | 62 | TCU (49) | Final | L | -7 |
| 25 | 2026-02-14 | Kansas (12) | 56 | 74 | Iowa State (5) | Final | W | 18 |
| 26 | 2026-02-16 | Houston (5) | 67 | 70 | Iowa State (7) | Final | W | 3 |
| 27 | 2026-02-21 | Iowa State (7) | 69 | 79 | BYU (21) | Final | L | -10 |
| 28 | 2026-02-24 | Iowa State (7) | 75 | 59 | Utah (112) | Final | W | 16 |
| 29 | 2026-02-28 | Texas Tech (14) | 82 | 73 | Iowa State (7) | Final | L | -9 |
| 30 | 2026-03-02 | Iowa State (9) | 57 | 73 | Arizona (3) | Final | L | -16 |
| 31 | 2026-03-07 | Arizona State (64) | 65 | 86 | Iowa State (9) | Final | W | 21 |
| 32 | 2026-03-11 | Arizona State (62) | 42 | 91 | Iowa State (9) | Final | W | 49 |
| 33 | 2026-03-12 | Iowa State (9) | 75 | 53 | Texas Tech (15) | Final | W | 22 |
| 34 | 2026-03-13 | Iowa State (9) | 80 | 82 | Arizona (3) | Final | L | -2 |
| 35 | 2026-03-20 | Tennessee State (157) | 74 | 108 | Iowa State (6) | Final | W | 34 |
| 36 | 2026-03-22 | Kentucky (30) | 63 | 82 | Iowa State (6) | Final | W | 19 |
| 37 | 2026-03-27 | Tennessee (24) | 76 | 62 | Iowa State (6) | Final | L | -14 |