Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-03 | New Hampshire (351) | 38 | 88 | Clemson (25) | Final | W | 50 |
| 2 | 2025-11-07 | Gardner-Webb (269) | 59 | 97 | Clemson (25) | Final | W | 38 |
| 3 | 2025-11-11 | Morehead State (298) | 56 | 83 | Clemson (25) | Final | W | 27 |
| 4 | 2025-11-15 | Clemson (25) | 74 | 79 | Georgetown (91) | Final | L | -5 |
| 5 | 2025-11-17 | North Alabama (141) | 61 | 81 | Clemson (25) | Final | W | 20 |
| 6 | 2025-11-21 | West Virginia (49) | 67 | 70 | Clemson (25) | Final | W | 3 |
| 7 | 2025-11-23 | Clemson (25) | 97 | 94 | Georgia (34) | Final/OT | W | 3 |
| 8 | 2025-11-28 | Alabama A&M (355) | 56 | 92 | Clemson (25) | Final | W | 36 |
| 9 | 2025-12-03 | Clemson (45) | 84 | 90 | Alabama (29) | Final | L | -6 |
| 10 | 2025-12-09 | Clemson (58) | 64 | 67 | BYU (12) | Final | L | -3 |
| 11 | 2025-12-13 | Mercer (106) | 63 | 70 | Clemson (58) | Final | W | 7 |
| 12 | 2025-12-16 | South Carolina (100) | 61 | 68 | Clemson (59) | Final | W | 7 |
| 13 | 2025-12-21 | Cincinnati (126) | 65 | 68 | Clemson (52) | Final | W | 3 |
| 14 | 2025-12-31 | Clemson (49) | 64 | 61 | Syracuse (82) | Final | W | 3 |
| 15 | 2026-01-03 | Clemson (49) | 73 | 68 | Pittsburgh (126) | Final | W | 5 |
| 16 | 2026-01-07 | SMU (17) | 70 | 74 | Clemson (37) | Final | W | 4 |
| 17 | 2026-01-10 | Clemson (37) | 76 | 61 | Notre Dame (71) | Final | W | 15 |
| 18 | 2026-01-13 | Boston College (178) | 50 | 74 | Clemson (28) | Final | W | 24 |
| 19 | 2026-01-17 | Miami (26) | 59 | 69 | Clemson (28) | Final | W | 10 |
| 20 | 2026-01-20 | North Carolina State (49) | 80 | 76 | Clemson (20) | Final/OT | L | -4 |
| 21 | 2026-01-24 | Clemson (20) | 77 | 63 | Georgia Tech (116) | Final | W | 14 |
| 22 | 2026-01-31 | Pittsburgh (134) | 52 | 63 | Clemson (28) | Final | W | 11 |
| 23 | 2026-02-04 | Clemson (31) | 66 | 64 | Stanford (62) | Final | W | 2 |
| 24 | 2026-02-07 | Clemson (31) | 77 | 55 | California (49) | Final | W | 22 |
| 25 | 2026-02-11 | Virginia Tech (52) | 76 | 66 | Clemson (29) | Final | L | -10 |
| 26 | 2026-02-14 | Clemson (29) | 54 | 67 | Duke (3) | Final | L | -13 |
| 27 | 2026-02-18 | Clemson (30) | 77 | 85 | Wake Forest (66) | Final | L | -8 |
| 28 | 2026-02-21 | Florida State (80) | 70 | 65 | Clemson (30) | Final | L | -5 |
| 29 | 2026-02-28 | Louisville (21) | 75 | 80 | Clemson (39) | Final | W | 5 |
| 30 | 2026-03-03 | Clemson (34) | 63 | 67 | North Carolina (19) | Final | L | -4 |
| 31 | 2026-03-07 | Georgia Tech (151) | 76 | 79 | Clemson (34) | Final | W | 3 |
| 32 | 2026-03-11 | Wake Forest (64) | 62 | 71 | Clemson (36) | Final | W | 9 |
| 33 | 2026-03-12 | Clemson (36) | 80 | 79 | North Carolina (20) | Final | W | 1 |
| 34 | 2026-03-13 | Clemson (36) | 61 | 73 | Duke (2) | Final | L | -12 |
| 35 | 2026-03-20 | Iowa (36) | 67 | 61 | Clemson (33) | Final | L | -6 |